EXCEF DS

Cefixime Trihydrate USP 100mg/5ml

Business Unit: Human

Medicine Type: Dry Syrup

Generic Name: Cefixime Trihydrate USP 100mg/5ml

Therapeutic Class: Third generation Cephalosporin antibiotic

Indication: Cefixime is a third generation semisynthetic cephalosporin antibiotic for oral administration. It is bactericidal against a broad spectrum of gram positive and gram negative bacteria at easily achievable plasma concentrations. It kills bacteria by interfering in the synthesis of bacterial cell wall. Cefixime is indicated in the treatment of the following infections when caused by the susceptible strains of the designated microorganisms: Uncomplicated urinary tract infections caused by Escherichia coli and Proteus mirabilis. Otitis Media caused by Haemophilus influenzae, Moraxella catarrhalis and Streptococcus pyogenes. Pharyngitis and tonsillitis caused by Streptococcus pyogenes. Acute bronchitis and acute exacerbations of chronic bronchitis caused by Streptococcus pneumoniae and Haemophilus influenzae. Uncomplicated gonorrhoea (cervical/urethral) caused by Neisseria gonorrhoeae.

Dosage & Administration: Children (6 month or older): Usually 8 mg/kg/day given as a single dose or in two divided doses or may be given as following ½-1 year: 75 mg daily. 1-4 years: 100 mg daily. 5-10 years: 200 mg daily. 11-12 years: 300 mg daily In typhoid fever, dosage should be 10 mg/kg/day for 14 days. Children (under 6 month): The safety and efficacy of Cefixime has not been established in children aged less than 6 months.

Preparation: Excef DS: 50ml powder for suspension