Flucloxacillin Sodium 125mg/5ml

Business Unit: Human

Medicine Type: Dry Syrup

Generic Name: Flucloxacillin Sodium 125mg/5ml

Therapeutic Class: Penicillinase-resistant penicillins

Indication: Flucloxacillin is active against Gram-positive organisms including penicillinase producing strains. It has little activity against Gram-negative bacilli. Flucloxacillin acts by inhibiting the formation of cell wall of bacteria. Flucloxacillin is indicated for the treatment of infections due to Gram-positive organisms, including infections caused by penicillinase producing staphylococci. These indications include: Skin and soft tissue infections: Boils, abscess, carbuncles, infected skin conditions (e.g. ulcer, eczema, acne, furunculosis, cellulitis, infected wounds, infected burns, otitis media and externa, impetigo). Respiratory tract infections: Pneumonia, lung abscess, empyema, sinusitis, pharyngitis, tonsillitis, quinsy. It is also used for the treatment of other infections i.e. osteomyelitis, enteritis, endocarditis, urinary tract infection, meningitis, septicaemia caused by Flucloxacillin-sensitive organisms. As a prophylactic agent, it is used during major surgical procedures where appropriate; for example, cardiothoracic and orthopedic surgery.

Dosage & Administration: Oral administration: Adult: 250 mg four times daily. Dosage may be doubled in severe infections. In osteomyelitis and endocarditis, up to 8 gm daily is used in 6-8 hourly divided doses. Children (2-10 years): 1/2 of adult dose. Children (Under 2 years): 1/4 of adult dose. Parenteral administration: Adult or Elderly: Intramuscular Injection: 250 mg four times daily. Intravenous Injection: 250 mg-1 g four times daily by slow injection over 3 to 4 minutes or by intravenous infusion. All systemic doses may be doubled in severe infections: doses up to 8 g daily have been suggested for endocarditis or osteomyelitis. Children: 2-10 years: half of the adult dose. Under 2 years: a quarter of the adult dose.

Preparation: Fluking® Powder for Suspension: Each carton contains a bottle having dry powder to reconstitute 100 ml suspension.