DRY SYRUP

Cephradine USP 125 mg/ 5 ml

Business Unit: Human

Medicine Type: Dry Syrup

Generic Name: Cephradine USP 125 mg/ 5 ml

Therapeutic Class: First Generation Cephalosporin Antibiotic

Indication: Abac (Cephradine) belongs to 1st Generation Cephalosporin group. It is effective for gram positive bacteria. This antibiotic is bacteriocidal in nature and works through inhibition of bacterial cell wall synthesis. It is indicated for :  Upper respiratory tract infections such as sinusitis, pharyngitis, tonsillitis, laryngo-tracheo bronchitis and otitis media.  Lower respiratory tract infections such as bronchitis (acute and chronic), lobar pneumonia and bronchopneumonia.  Urinary tract infections including cystitis, urethritis and pyelonephritis.  Skin and soft tissue infections such as- abscess, cellulitis, furunculosis and impetigo.

Dosage & Administration: Adults:  Urinary tract infections: 500 mg four times daily or 1 g twice daily. Infections which are severe or chronic may necessitate the administration of higher doses.  Respiratory tract infections: 250 to 500 mg four times daily or 500 mg to 1 g twice daily, dependent on the site and severity of the infection.  Skin and soft tissue infections: 250 to 500 mg four times daily or 500 mg to 1 g twice daily, again dependent on the site and severity of the infection. Children:  Total daily dose of 25 to 50 mg/kg given in two or four equally divided doses.  Otitis media: Total daily dose of 75 to 100 mg/kg given in divided doses 6 to 12 hourly.  Maximum daily dosage: 4 gm

Preparation: 100 ml Dry Syrup

Erythromycin Ethyl Succinate USP 125mg/5ml

Business Unit: Human

Medicine Type: Dry Syrup

Generic Name: Erythromycin Ethyl Succinate USP 125mg/5ml

Therapeutic Class: Anti Bacterial

Indication: It belongs to the macrolides group of antibiotics. It kills bacteria by inhibiting protein synthesis process of bacteria. Zerobac (Erythromycin) is the drug of choice in the following indications-  Alternative to a penicillin in penicillin-sensitive patients, penicillin-resistant staphylococcal infections, alternative to a tetracycline in mycoplasma pneumonia.  Pertussis diphtheria-especially in treatment of the carrier state.  Rheumatic fever prophylaxis.  Chronic bronchitis.  Otitis media.  Chronic prostatitis.

Dosage & Administration: Adults: The usual dose is 1-2 gm daily in divided doses. This may be increased up to 4 gm per day according to the severity of the infection. Children: The usual regimen is 30-50 mg/kg/day. In severe cases the dose may be doubled.

Preparation: A bottle containing 100 ml syrup and a measuring cup.

Cefpodoxime Proxetil 40 mg/5 ml

Business Unit: Human

Medicine Type: Dry Syrup

Generic Name: Cefpodoxime Proxetil 40 mg/5 ml

Therapeutic Class: Third Generation Cephalosporins

Indication: Cefpodoxime is known as a cephalosporin antibiotic. It works by stopping the growth of bacteria. Cefpodoxime treats only bacterial infections. Podoxi (Cefpodoxime Proxetil USP) is indicated for the treatment of infections caused by susceptible microorganism, listed below: Acute otitis media, Pharyngitis/tonsillitis, Acute maxillary sinusitis, Community acquired pneumonia, Acute bacterial exacerbation of chronic bronchitis, Skin and skin structure infections, Uncomplicated urinary tract infections, Uncomplicated gonorrhea, Rectal gonococcal infections in women.

Dosage & Administration: Adults and Adolescents (13 years and older) • Pharyngitis/tonsillitis: 100 mg 12 hourly, 5 to 10 days • Acute maxillary sinusitis: 200 mg 12 hourly, 10 day • Community acquired pneumonia: 200 mg 12 hourly, 14 days • Acute bacterial exacerbations of chronic bronchitis: 200 mg 12 hourly, 10 days • Skin and skin structure: 400 mg 12 hourly, 7 to 14 days • Uncomplicated urinary tract infection: 100 mg 12 hourly, 7 days • Uncomplicated gonorrhea: single dose of 200 mg • Rectal gonococcal infections in women: single dose of 200 mg Infants and Pediatric Patients (2 months to 12 years) • Acute otitis media: 5 mg/kg body weight 12 hourly, 5 days • Pharyngitis /tonsillitis: 5 mg/kg body weight 12 hourly, 5 to 10 days • Acute maxillary sinusitis: 5 mg/kg body weight 12 hourly, 10 days

Preparation: 50 ml Dry Syrup

Ciprofloxacin USP 250 mg/5 ml

Business Unit: Human

Medicine Type: Dry Syrup

Generic Name: Ciprofloxacin USP 250 mg/5 ml

Therapeutic Class: Anti-diarrhoeal Antimicrobial drugs

Indication: Ciprofloxacin is a fluoroquinolone antibiotic. It is bactericidal antibiotic. it is used to treat different types of bacterial infections Cipro-C (Ciprofloxacin) is indicated for the treatment of Respiratory Tract Infections, Urinary tract infections, Pelvic Inflammatory Diseases, Infectious Diarrhea (Shigella dysenteriae, Vibrio cholera), Typhoid fever, Intra-abdominal infections, Prostatitis, Skin and Soft Tissue Infections, Bone and Joint Infections, Gonorrhea, Neutropenic patients with fever due to bacterial infection, Meningitis, Surgical prophylaxis.

Dosage & Administration: Suspension: Pediatric: 10-20 mg/kg (max. 750 mg) twice daily (10 to 21 days). The duration of therapy depends on the type and severity of infection.

Preparation: 60 ml Dry Syrup

Cefuroxime Axetil USP 125 mg/5 ml

Business Unit: Human

Medicine Type: Dry Syrup

Generic Name: Cefuroxime Axetil USP 125 mg/5 ml

Therapeutic Class: Second generation Cephalosporins

Indication: Cefuxet (Cefuroxime axetil) is indicated for the treatment of infections caused by sensitive bacteria like Pharyngitis/Tonsillitis, Acute Bacterial Otitis Media, Acute bacterial maxillary sinusitis, Lower respiratory tract infections including pneumonia, Acute bacterial exacerbation of chronic bronchitis and Secondary bacterial infections of Acute bronchitis, Skin and skin-structure infections, Urinary tract infections, Bone and Joint Infections, Gonorrhea, Early Lyme Disease.

Dosage & Administration: Tablet or Suspension- Adolescents and adults (13 years and older)- • Pharyngitis/tonsillitis: 250 mg b.i.d. for 5-10 days • Acute bacterial maxillary sinusitis: 250 mg b.i.d. for 10 days • Acute bacterial exacerbation of chronic bronchitis: 250-500 mg b.i.d. for 10 days • Secondary bacterial infections of acute bronchitis: 250-500 mg b.i.d. for 5-10 days • Uncomplicated skin and skin structure infections: 250-500 mg b.i.d. for 10 days • Uncomplicated urinary tract infections: 250 mg b.i.d. for 7-10 days • Uncomplicated Gonorrhea: 1000 mg Single dose • Community acquired pneumonia: 250-500 mg b.i.d. for 5-10 days • MDR Typhoid Fever: 500 mg b.i.d. for 10-14 days • Early Lyme disease: 500 mg b.i.d. for 20 days Pediatric Patients (3 months to 12 years)- • Pharyngitis/Tonsillitis: 20 mg/kg/day b.i.d for 5-10 days • Acute otitis media: 30 mg/kg/day b.i.d for 10 days • Acute bacterial maxillary sinusitis: 30 mg/kg/day b.i.d for 10 days • Impetigo: 30 mg/kg/day b.i.d for 10 days

Preparation: 70 ml Dry Syrup

Azithromycin 200mg/5ml

Business Unit: Human

Medicine Type: Dry Syrup

Generic Name: Azithromycin 200mg/5ml

Therapeutic Class: Macrolide Antibiotic

Indication: It is belongs to macrolid group . It kills bacteria by inhibiting protein synthesis process of bacteria . Azithin (Azithromycin) is indicated for  Enteric Fever/ Typhoid Fever  RTIs (Respiratory Tract Infections especially Tonsillitis)  UTIs (Urinary Tract Infections)  Acute Otitis Media  SSTIs (Skin and Soft Tissue Infections)  STDs (Sexually Transmitted Diseases)

Dosage & Administration:  Adult: 500 mg Once daily orally for 7 days or more depending on the indication. For STDs: 1 gm orally as a single dose.  Children's (Over 6 months): 10 mg/kg orally once daily for 5 to 7 days.

Preparation: 15 ml, 35 ml & 50 ml Dry Syrup.

Flucloxacillin Sodium 125mg/5ml

Business Unit: Human

Medicine Type: Dry Syrup

Generic Name: Flucloxacillin Sodium 125mg/5ml

Therapeutic Class: Penicillinase-resistant penicillins

Indication: Flucloxacillin is active against Gram-positive organisms including penicillinase producing strains. It has little activity against Gram-negative bacilli. Flucloxacillin acts by inhibiting the formation of cell wall of bacteria. Flucloxacillin is indicated for the treatment of infections due to Gram-positive organisms, including infections caused by penicillinase producing staphylococci. These indications include: Skin and soft tissue infections: Boils, abscess, carbuncles, infected skin conditions (e.g. ulcer, eczema, acne, furunculosis, cellulitis, infected wounds, infected burns, otitis media and externa, impetigo). Respiratory tract infections: Pneumonia, lung abscess, empyema, sinusitis, pharyngitis, tonsillitis, quinsy. It is also used for the treatment of other infections i.e. osteomyelitis, enteritis, endocarditis, urinary tract infection, meningitis, septicaemia caused by Flucloxacillin-sensitive organisms. As a prophylactic agent, it is used during major surgical procedures where appropriate; for example, cardiothoracic and orthopedic surgery.

Dosage & Administration: Oral administration: Adult: 250 mg four times daily. Dosage may be doubled in severe infections. In osteomyelitis and endocarditis, up to 8 gm daily is used in 6-8 hourly divided doses. Children (2-10 years): 1/2 of adult dose. Children (Under 2 years): 1/4 of adult dose. Parenteral administration: Adult or Elderly: Intramuscular Injection: 250 mg four times daily. Intravenous Injection: 250 mg-1 g four times daily by slow injection over 3 to 4 minutes or by intravenous infusion. All systemic doses may be doubled in severe infections: doses up to 8 g daily have been suggested for endocarditis or osteomyelitis. Children: 2-10 years: half of the adult dose. Under 2 years: a quarter of the adult dose.

Preparation: Fluking® Powder for Suspension: Each carton contains a bottle having dry powder to reconstitute 100 ml suspension.

Cefixime Trihydrate USP 100mg/5ml

Business Unit: Human

Medicine Type: Dry Syrup

Generic Name: Cefixime Trihydrate USP 100mg/5ml

Therapeutic Class: Third generation Cephalosporin antibiotic

Indication: Cefixime is a third generation semisynthetic cephalosporin antibiotic for oral administration. It is bactericidal against a broad spectrum of gram positive and gram negative bacteria at easily achievable plasma concentrations. It kills bacteria by interfering in the synthesis of bacterial cell wall. Cefixime is indicated in the treatment of the following infections when caused by the susceptible strains of the designated microorganisms: Uncomplicated urinary tract infections caused by Escherichia coli and Proteus mirabilis. Otitis Media caused by Haemophilus influenzae, Moraxella catarrhalis and Streptococcus pyogenes. Pharyngitis and tonsillitis caused by Streptococcus pyogenes. Acute bronchitis and acute exacerbations of chronic bronchitis caused by Streptococcus pneumoniae and Haemophilus influenzae. Uncomplicated gonorrhoea (cervical/urethral) caused by Neisseria gonorrhoeae.

Dosage & Administration: Children (6 month or older): Usually 8 mg/kg/day given as a single dose or in two divided doses or may be given as following ½-1 year: 75 mg daily. 1-4 years: 100 mg daily. 5-10 years: 200 mg daily. 11-12 years: 300 mg daily In typhoid fever, dosage should be 10 mg/kg/day for 14 days. Children (under 6 month): The safety and efficacy of Cefixime has not been established in children aged less than 6 months.

Preparation: Excef DS: 50ml powder for suspension

Clarithromycin USP 125mg/5ml

Business Unit: Human

Medicine Type: Dry Syrup

Generic Name: Clarithromycin USP 125mg/5ml

Therapeutic Class: Macrolide Antibiotic

Indication: Rith is a preparation of Clarithromycin USP which is a broad-spectrum macrolide antibiotic. It is bacteriostatic in nature and works by inhibiting the Bacterial Protein synthesis through binding with bacterial 50s ribosomal subunits. Rith is indicated in upper respiratory tract infection (sinusitis, pharyngitis), lower respiratory tract infection (acute and chronic bronchitis, pneumonia, atypical pneumonia, Community-acquired pneumonia), skin and soft tissue infection, adjunct in the treatment of duodenal ulcers to eradicate of Helicobacter pylori.

Dosage & Administration: Children: Bodyweight under 8 kg: 7.5 mg/kg twice daily. Bodyweight of 8-11 kg (1-2 years): 2.5 ml (Half teaspoonful) twice daily. Bodyweight of 12-19 kg (3-6 years): 5 ml (One teaspoonful) twice daily. Bodyweight of 20-29 kg (7-9 years): 7.5 ml (One & half teaspoonfuls) twice daily. Bodyweight of 30-40 kg (10-12 years): 10 ml (Two teaspoonfuls) twice daily.

Preparation: Rith PFS: 60ml PFS